Информация об авторах
Whitfield-Gabrieli S1, Ford JM.
Отдел мозга и когнитивных наук, Массачусетский технологический институт, Кембридж, Массачусетс 02139, США.
Выдержка
Нейропсихиатрические расстройства связаны с аномальной функцией сети режима по умолчанию (DMN), распределенной сетью областей мозга, более активными во время отдыха, чем при выполнении многих задач, требующих внимания и характеризующихся высокой степенью функциональной связности (т.е. Временными корреляциями между областями мозга). Исследование функционального магнитного резонанса показало, что DMN в здоровом мозге ассоциируется с независимой от стимула мышлением и саморефлексией и что большее подавление DMN связано с лучшими характеристиками в задачах, требующих внимания. При шизофрении и депрессии DMN часто оказывается гиперактивированным и гиперсвязным. При шизофрении это может относиться к чрезмерно интенсивной самореференции и нарушениям внимания и рабочей памяти. При депрессии гиперактивность DMN может быть связана с отрицательным гаммамированием. Эти результаты рассматриваются в терминах того, что известно о психологических функциях, поддерживаемых DMN, и изменении DMN при других нейропсихиатрических расстройствах.
Источник: https://www.ncbi.nlm.nih.gov/pubmed/22224834
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